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First published online February 16, 2009
British Journal of Radiology (2009) 82, 561-570
© 2009 British Institute of Radiology
doi: 10.1259/bjr/27721218
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British Journal of Radiology 82 (2009),561-570 ©2009 The British Institute of Radiology

320-slice CT neuroimaging: initial clinical experience and image quality evaluation

E SIEBERT, MD 1 G BOHNER, MD 1 M DEWEY, MD 2 F MASUHR, MD 3 K T HOFFMANN, MD 1 J MEWS 4 F ENGELKEN, MD 2 H C BAUKNECHT, MD 2 S DIEKMANN, MD 1 and R KLINGEBIEL, MD 1

Departments of 1 Neuroradiology, 2 Radiology and, 3 Neurology, Charité Universitary Medicine, Berlin, Germany, and 4 Toshiba Medical Systems, Neuss, Germany

Correspondence: Eberhard Siebert, Department of Neuroradiology, Charité Universitary Medicine Berlin, Charitéplatz 1, 10117 Berlin, Germany. E-mail: eberhard.siebert{at}charite.de

The aim of this study was to report initial clinical experience with a 320-slice CT scanner and to perform an image quality evaluation. 26 patients with presumptive cerebrovascular pathology underwent 320-slice CT. Single-rotation CT of the head, incremental CT angiography (three-dimensional (3D) CTA) as well as four-dimensional whole-brain CTA (4D CTA) and whole-brain CT perfusion (CTP) were performed and the resulting images were assessed for quality and compared with those obtained with 64-slice CT protocols. 320-slice CT neuroimaging could be performed in all cases. The image quality of 320-slice CT of the head and 3D CTA was inferior to that of the 64-slice protocols. The image quality of 4D 320-slice CTA was rated as inferior to both 320- and 64-slice 3D CTA. 4D CTA-CTP imaging added information with pivotal clinical implications. 320-slice CT neuroimaging is feasible technique that permits whole-brain 4D imaging and has the potential to identify pathologies with altered haemodynamics. However, image quality is a limitation of this technique at present.






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