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Figure 3. A gross tumour volume on CT scan in a patient with oropharyngeal carcinoma, and biological target volume on the corresponding 64Cu-diacetyl-bis(N(4)-methylthiosemicarbazone) (60Cu-ATSM) image. Reproduced with kind permission from: Chao KS, Bosch WR, Mutic S, et al. A novel approach to overcome hypoxic tumor resistance: Cu-ATSM-guided intensity-modulated radiation therapy. Int J Radiat Oncol Biol Phys 2001;49:1171–82.





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