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Figure 6. Problems with accurate delineation of target volumes as a result of respiratory motion during emission acquisition. (a) Tumour extent during a respiratory average frame. (b) Tumour extent in a respiratory-gated frame. (c) Planning target volume (PTV) from the gated and non-gated PET frames. Reprinted with permission of the Society of Nuclear Medicine from: Nehmeh S, Erdi Y, Ling CC, et al. Effect of respiratory gating on quantifying PET images of lung cancer. J Nucl Med 2002;43:87681.