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Figure 4. Integrated 18F-azomycin arabinoside (FAZA)-PET/CT in a patient with larynx squamous cell carcinoma. The PET/CT image fusion ((a) axial; (b) coronal; (c) intensity-modulated radiotherapy dose painting). The hypoxic area (biological target volume) is treated with 2.4 Gy/fraction; the gross tumour volume, based on radiological and clinical data is treated with 2 Gy/fraction. However, the validity of this hypothesis has to be evaluated in future trials. The FAZA-PET/CT studies were performed in co-operation with the Section of Radiopharmacy, University Tübingen, Prof. Dr H J Machulla, and the Department of Nuclear Medicine, Technical University Munich, Prof. Dr M Schwaiger, Germany. *In this picture the left and right side are changed.