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Figure 1. Patient with prostate cancer investigated using an integrated PET/CT. Upper-left: choline-PET/CT image fusion based on three-dimensional (3D) coordinates. Upper-right: choline-PET. The pathological choline uptake could help to visualise the gross tumour mass in the prostate. Below: CT before PET and CT after PET, co-registered using 3D coordinates, documenting the patient's movements during the investigations, which raise concerns about the accuracy of the PET/CT image fusion using integrated PET/CT and data co-registration based on 3D coordinates.