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Figure 1. 51-year-old man with sarcoidosis. (a) Current CT image shows a focal area of mass-like consolidation with air-filled cavities in the right lung. Multiple nodules and nodular thickening in the peribronchovascular bundles are also seen in both lungs. (b) Temporal subtraction image shows increase in size of the air-filled cavities (arrows). Black areas indicate increase in size of the cavities. (c) Warped previous CT image (the extrapulmonary compartment is excluded). Most structures of both lungs are well matched with those of the current CT image. (d) Original previous CT image. Although the lesions in the right lung are matched with those of the current image, most structures of the left lung are not matched with those of the current CT image. Registration is performed three-dimensionally (non-rigidly). (c) The warped previous CT image was produced from the previous CT images, not only from (d) the single previous CT image.
