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Figure 2. A 62-year-old man with acute myelogenous leukaemia (AML) presented with fever and cough. Chest CT shows a large infiltration the right lower lobe, already extending into the middle lobe. (a) Good demarcation of a huge lung sequester (black arrow), surrounded by peripheral inflammation is seen on axial CT-scan. (b) Contrast enhanced CT (CECT) demonstrates the extent of pulmonary infarction (white arrow) by showing no contrast enhancement. (c) At histology, large area of lung parenchymal necrosis, due to invasion of large pulmonary vessels by fungi, was found. Thrombotic occlusion of pulmonary vessels (Elastica van Giesson stain x 200 magnification) due to Rhizopus hyphae (white arrow) are seen. Note also normally air filled neighbouring alveoli. (d) 10 days after erythematous lesions of the legs caused by mucormycosis had occurred; a fluid collection with ring enhancement (white arrow) was diagnosed in the left iliopsoas bursa.
