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Figure 1. Patient 1: contrast enhanced CT prior to treatment with imatinib. (a) The primary gastrointestinal stromal tumour (GIST) (outlined) involves the duodenum and pancreatic head and measures 9.3 cm. (b) No liver metastases are visible at this level, although three subtle lesions were seen elsewhere in the liver. Patient 1: contrast enhanced CT after 8 weeks of treatment with imatinib. (c) The duodenal mass (outlined) has reduced in size to 7.4 cm. (d) Multiple small low-density lesions are now seen within the liver (same level as Figure 1b). These were initially reported as being new metastases, but subsequently were considered as being due to cystic change in pre-existing metastases.
