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Figure 6. Dynamic perfusion characterization. In this time-course diagram, the black triangles show an example of repeated acquisition at multiple inversion time points. Usually, a three-parameter fit model is applied [37] to estimate cerebral blood flow (CBF) when multiple inversion times arterial spin labelling (ASL) sequences are used, which reveal additional information about arrival time and bolus duration. The second time-course (white triangles) has been calculated with identical perfusion parameters, while taking into account a Look-Locker readout method [43, 45, 124] (flip angle = 30°). The advantage of this method is a higher signal to noise ratio (SNR) as per acquisition time.
