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Figure 6. Cartoon of the molecular structure of vascular endothelial growth factor (VEGF). VEGF is potent angiogenic peptide that induces endothelial cell growth as well as increasing the permeability of blood vessels. VEGF is typically over-expressed by tumours and is a principal factor in the altered vascularity of tumours. It is also the target of several molecularly targeted anti-angiogenic therapies. The image was obtained from http://www.rcsb.org/pdb/.
