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Figure 1. Clinical stage T2b prostate cancer. (a) Axial T2 weighted MR image demonstrates a large low signal intensity area in the left peripheral zone with obliteration of the rectoprostatic angle (arrow), indicating left side extracapsular invasion. (b) MR spectra show large-volume disease (all eight voxels are abnormal) with absence of citrate and marked elevation of choline, indicating high-grade disease. (c) Step-section pathology confirms large-volume tumour with left side extracapsular extension. Pathology stage pT3a, Gleason grade 4+3.





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