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Figure 3. Hypervascular metastasis. (a) There is a large part-solid, part-cystic lesion in the mid portion of the right lobe of the liver demonstrated on ultrasound. This lesion was identified 8 years following the original mastectomy on routine follow up. (b) The liver is now imaged using a continuous low mechanical index harmonic package following the injection of 2.4 ml of Sonovue (Bracco, Milan, Italy). This image was obtained during the arterial phase of enhancement. There is a hypervascular solid rim to the lesion. This rim became hypoechoic during the sinusoidal phase, a feature of malignancy. The lesion was biopsied, and this confirmed adenocarcinoma of the same cell type as the primary breast carcinoma.