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Figure 1. Small liver metastasis. (a) Standard liver ultrasound in a patient with a history of carcinoma of the breast. No focal abnormality was detected. (b) Following the injection of microbubble contrast media, a small 7 mm hypoechoic focus can be identified in the parenchymal phase of liver enhancement. (c) Standard T1 weighted MR. There is a small low signal lesion in the posterior aspect of the right lobe of the liver. (d) Standard T2 weighted MR. The lesion can just be identified on this sequence. (e) T2 fat saturation breath hold MR. The small lesion now has an increased signal. (f) A sub-10 mm liver metastasis (arrow) is clearly visible on this T2 weighted post-iron oxide MR image of the liver. Post-iron oxide (Endorem; Guerbet, Paris) MR is the most sensitive non-invasive method of identifying liver metastasis.