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Figure 2. Case 1, "chasing" toxicity diffusion weighted imaging/apparent diffusion coefficient (DWI/ADC) images of the brain. (a) Initial presentation, showing no areas of restricted diffusion; no matching areas of increased DWI signal and decreased ADC signal. (b) 6 month follow-up, showing areas of increased water motion corresponding to areas of high T2W signal seen in Figure 1a. The areas of corresponding increased DWI and ADC signal signify areas of increased water diffusion. In such cases, the increased DWI signal is presumably due to "T2 shine-through" effect.