Click on image to view larger version.
Figure 3. Association of the measured capillary permeability in the locally advanced rectal cancers in our study with response following chemotherapy. The association indicates that tumours exhibiting a greater capillary permeability (as measured by Ktrans) are more likely to respond to treatment than those that are not. If this association does reflect underlying biology then it may be related to drug delivery. Alternatively it may simply be reflecting a particularly susceptible phenotype. Ktrans is expressed as the logarithm since the transform resulted in a normal distribution of the data.
