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Figure 9. Scattergram showing the distribution of the values of ve and Ktrans for a group of gliomas (squares), meningiomas (diamonds) and vestibular schwannomas (triangles). Note that vestibular schwannomas can be distinguished by increase in extravascular extracellular space fraction and that more aggressive forms of meningioma and glioma are characterized by higher values of Ktrans. This analysis was performed using a standard 2-compartment pharmacokinetic model.