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Figure 7. Agent detection imaging (ADI). The grey-scale scan in this patient with a known malignancy shows two areas suspicious for metastases (arrowheads in (a)). In the ADI mode, obtained several minutes after injection of a liver-specific contrast agent, these lesions are more clearly seen but additional lesions that were not apparent appear (arrows in (b)). The effect depends on the destruction of microbubbles that fill the microcirculation of the normal liver but rapidly wash out of the tumour's microcirculation.