Figure 4. The use of the ligand ¹¹C-WAY100635 to measure the amount of the drug pindolol needed to be administered to achieve blockade of the 5HT_1A receptor [6]. (a) Pindolol occupancy of pre-synaptic and post-synaptic 5-HT1A receptors. (b) ¹¹C-WAY100635 binding before and after 20 mg of pindolol. Reproduced with the kind permission of Professor P Grasby and Elsevier Science.

Return to article