Click on image to view larger version.
Figure 5 Iodinated contrast media accelerates apoptosis in lipopolysaccharide (LPS) stimulated neutrophils. Neutrophils were cultured in Rosweli Park Memorial Institute 1640 medium containing 10% platelet poor plasma alone and treated with iohexol 40 mg I ml-1, with or without LPS (1000 ng ml-1). Apoptosis was assessed at 1 h, 12 h and 24 h by flow cytometry. Results expressed as mean percentage of apoptotic cells±standard error of the mean; n=4; *p<0.01 for LPS treated vs control neutrophils; 
p<0.01 for iohexol treated vs control; 
p<0.01 for LPS+iohexol vs LPS alone. –
–, control; –
–, iohexol; –
–, LPS; –
–, LPS+iohexol.
