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Figure 1. Time course of apoptosis induced by iodinated contrast media (ICM). (a) Representative flow cytometry profiles taken at 12 h culture of annexin v-fluorescein isothiocyanate (V-FITC) and propidium iodide staining of: (A), control; (B) iotrolan 20 mg I ml-1; (C) iohexol 20 mg I ml-1; (D) ioxaglate 20 mg I ml-1; (E), diatrizoate 20 mg I ml-1. The percentage given in the top left quadrant indicate the percentage of annexin V-FITC positive apoptotic neutrophils. (b) Results expressed as mean percentage of apoptotic cells±standard error of the mean. *, p<0.05 and {ddagger}, p<0.01 for ICM treated vs control neutrophils.





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