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Multi-organ involvement: lessons from the experience of one victim of the Tokai-mura criticality accident

Hematopoietic Cell Transplantation Team, Division of Hematology, the Institute of Medical Sciences, the University of Tokyo. 6-1, 4 Shirokanedai, Minato-ku, Tokyo 108, Japan

View larger version (22K): [in a new window]   Figure 1. Changes in haematological data pre transplant. BM, bone marrow; WBC, white blood cells; RET, reticulocytes; LYM, lymphocytes; PLAT, platelets; rhG-CSF, recombinant human granulocyte-colony-stimulating factor; CBT, cord blood transplantation.

View larger version (42K): [in a new window]   Figure 2. Clinical course post transplant: changes in (a) blood leukocyte numbers and (b) haemoglobin level and blood platelet numbers. WBC, white blood cells; ANC, absolute neutrophil count; CBT, cord blood transplantation; TNC, total nucleated cell count; mPSL, methylprednisolone; CyA, cyclosporine A; ATG, antithymocyte globulin; G-CSF, granulocyte colony-stimulating factor; Lym, lymphocytes; Hb, haemoglobin; TPO, thrombopoietin.

View larger version (20K): [in a new window]   Figure 3. Time-scale of onset of tissue damage and skin transplantation.

View larger version (70K): [in a new window]   Figure 4. Mucodermal damage (A) 1 month and (B,C) 2 months after the accident.