This Article Abstract Full Text Full Text (PDF) Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Akashi, M Search for Related Content PubMed PubMed Citation Articles by Akashi, M

Role of infection and bleeding in multiple organ involvement and failure

Department of Radiation Emergency Medicine, Research Center for Radiation Emergency Medicine, National Institute of Radiological Sciences, 263-8555 Japan

View larger version (38K): [in a new window]   Figure 1. Inflammation cascade following major stress leading to multiple organ failure. ROS, reactive oxygen species; PMN, polymorphonuclear neutrophils; DIC, disseminated intravascular coagulation. Adopted and modified from Riedemann et al [8].

View larger version (48K): [in a new window]   Figure 2. Balance of inflammation and anti-inflammation.

View larger version (31K): [in a new window]   Figure 3. Role of blood vessel injury in multiple organ failure (MOF). The endothelial cell damage and release of tissue factor may be important in the development of MOF. Adopted and modified from Kidokoro et al [29].

View larger version (29K): [in a new window]   Figure 4. Possible mechanisms for multiple organ failure in radiation exposure. CARS, compensatory anti-inflammatory response syndrome.