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British Journal of Radiology (2005) Supplement_27, 1-8
© 2005 British Institute of Radiology
doi: 10.1259/bjr/77700378

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Multi-organ involvement as a pathogenetic principle of the radiation syndromes: a study involving 110 case histories documented in SEARCH and classified as the bases of haematopoietic indicators of effect

T M Fliedner, MD, H D Dörr, MD and V Meineke, MD

Radiation Medicine Research Group, Faculty of Medicine, University of Ulm, Germany



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Figure 1. Indicators of irreversible injury (haematological grade H4). Granulocytes; initial granulocytosis and progressive decline of cell counts between day 4 and day 6. Lymphocytes: progressive decline within 24 h. Platelets: progressive decline within the first 10 days.

 


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Figure 2. Indicators of reversible injury (haematological grade H3). Granulocytes: moderate granulocytosis, decline between day 4 and day 10, abortive recovery followed by nadir days 20–30. Lymphocytes: decline to nadir levels within 2 days, slow recovery thereafter. Platelets: initial 10-day shoulder followed by decline towards day 20, nadir days 20–30.

 





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