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British Journal of Radiology (2009) 82, e15-e19
© 2009 British Institute of Radiology
doi: 10.1259/bjr/30768802

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Primary malignant lymphoma of the gallbladder: a case report and literature review

A ONO, MD 1 S TANOUE, MD, PhD 2 Y YAMADA, MD 2 Y TAKAJI, MD 3 F OKADA, MD, PhD 2 S MATSUMOTO, MD, PhD 2 and H MORI, MD, PhD 2

1 Department of Radiology, Oita Prefectural Hospital, Bunyo, 476, Oita-shi, Oita, 870–0855, 2 Department of Radiology, Oita University Faculty of Medicine, Idaigaoka, 1-1, Hasama-machi, Yufu-shi, Oita, 879–5593, 3 Department of Radiology, Oita Tobu Hospital, Shimura, 765, Oita-shi, Oita, 870–0261, Japan


Figure 1
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Figure 1. Pre-operative CT findings. (a) Pre-contrast CT demonstrates no calcified stones within the gallbladder cavity. (b,c) Dynamic CT shows laminar enhancement on the mucosal surface of the gallbladder wall (black arrows). Abnormal attenuation areas can be seen along the intrahepatic portal vein (white arrows) ((b) arterial phase; (c) parenchymal phase). (d) Multiple lymph node swelling can also be seen in the hepatoduodenal ligament (arrowheads).

 

Figure 2
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Figure 2. MRI findings. The gallbladder lesion shows low signal intensity on(a) a T1 weighted sequence and high intensity on (b) a T2 weighted sequence compared with the signal intensity of the liver parenchyma (b) (white arrows).

 

Figure 3
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Figure 3. Histological findings(haematoxylin and eosin staining). (a) Lymphocytes have infiltrated into the submucosa, muscularis and subserosa of the gallbladder wall (the loupe image). (b) Tumour cells are atypical lymphocytes and form lymphoid follicles (x200 and x400 (inset)).

 





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