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Designing equivalent treatment regimens for prostate radiotherapy based on equivalent uniform dose

¹ Department of Radiation Oncology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, ² Department of Radiation Medicine, Ohio State University, Columbus, OH 43210, ³ School of Health Sciences, Purdue University, West Lafayette, IN 47907-1338, ⁴ Department of Radiation Oncology, Cooper Health System, One Cooper Plaza, Camden, NJ 08103, USA

View larger version (19K): [in this window] [in a new window]   Figure 1. Representative dose–volume histograms of prostate and rectum for external beam radiotherapy (EBRT) and brachythrerapy (BT).

View larger version (20K): [in this window] [in a new window]   Figure 2. Combinations of external beam radiotherapy(EBRT)and I-125 permanent brachytherapy that yield a fixed EUD of 70 Gy or 81 Gy. The data were generated with /β = 3.1 Gy, = 0.15 Gy–1, Tr = 16 min and Td = 42 days.