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Monitoring rheumatoid arthritis synovitis with ^99mTc-anti-CD3

¹ Departamento de Radiologia and ² Departamento de Clínica Médica, Universidade Federal do Rio de Janeiro, Faculdade de Medicina, Hospital Universitário Clementino Fraga Filho, Rio de Janeiro, ³ Universidade Federal de Minas Gerais, Departamento de Clínica Médica, Juiz de Fora, Brazil

View larger version (54K): [in this window] [in a new window]   Figure 1. Normal pattern of99mTc–OKT3 scintigraphy of the knees in a patient with RA. Scans were obtained (a) 1 h and (b) 3 h after endovenous injection of the radiopharmaceutical in a patient with medium activity disease (according to DAS-28). The images show no areas of uptake.

View larger version (42K): [in this window] [in a new window]   Figure 2. Patient with RA classified as high-activity disease, according to DAS-28. 99mTc–OKT3 scintigraphy of the knees shows areas of uptake in these joints (a) 1 h and (b) 3 h after endovenous injection of the radiopharmaceutical.