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British Journal of Radiology (2007) 80, S49-S55
© 2007 British Institute of Radiology
doi: 10.1259/bjr/25927054

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Human mesenchymal stem cells home specifically to radiation-injured tissues in a non-obese diabetes/severe combined immunodeficiency mouse model

M Mouiseddine S François A Semont A Sache B Allenet N Mathieu J Frick D Thierry and A Chapel

Laboratoire Thérapie Cellulaire et Radioprotection Accidentelle, Institut de Radioprotection et de Sûreté Nucléaire (IRSN), BP n°17, F-92262 Fontenay aux Roses CEDEX, France


Figure 1
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Figure 1. In vitro differentiation of human mesenchymal stem cells (hMSC). The cultured hMSC could enter different cell lineages such as osteogenic (2), chondrogenic (3) and adipogenic (4) lineages. Undifferentiated control (1).

 

Figure 2
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Figure 2. Localization of hMSC into abdominal irradiated areas of NO/SCID mice. Human MSC were localized into (a) muscularis externa stomach and (b) into mucosa stomach (black arrows).

 





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