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British Journal of Radiology (2007) 80, e212-e215
© 2007 British Institute of Radiology
doi: 10.1259/bjr/90471387
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Radiation-induced skull base leiomyosarcoma presenting with intracerebral haemorrhage

C-H Toh, MD 1 H-F Wong, MD 1 S-M Jung, MD 2 and A-M Wong, MD 1

Departments of 1 Medical Imaging and Intervention and 2 Pathology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 5 Fu Hsing Street, Kwei Shan Hsiang, Tao-Yuan 333, Taiwan


Figure 1
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  		Figure 1. (a) Axial CT with contrast enhancement reveals a soft tissue mass arising from and destroying the greater wing of right sphenoid, extending into orbital apex and middle cranial fossa. A hyperdense hematoma is found in adjacent temporal lobe. The sellar is enlarged with empty sella appearance due to previous surgery. (b) Higher section shows extension of the hematoma to the right striatocapsular region and subfalcine herniation. There is evidence of previous craniotomy for pituitary macroadenoma with bony defect at right temporal bone.

 

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  		Figure 2. Contrast-enhanced T1 weighted MR image performed after surgical removal of right intracerebral hematoma demonstrating heterogenous enhancement of the mass. There is little residual hematoma in right temporal lobe.

 

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  		Figure 3. Photomicrography of a tissue sample showing proliferation of highly pleomorphic spindle cells with anaplastic nuclei, mitoses and necrosis. H&E. Original magnifications x400.

 




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