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Evolution of lung nodules 5 mm detected with low-dose CT in asymptomatic smokers

¹ School of Medicine, University of Milano, 7 Via Festa del Perdono, 20122 Milan, Italy, Departments of ² Radiology, ³ Thoracic Surgery and ⁴ Epidemiology and Biostatistics, European Institute of Oncology, 435 Via Ripamonti, 20141 Milan, Italy

View larger version (80K): [in this window] [in a new window]   Figure 1. (a) Small solid lung nodule (maximum axial diameter 4.9 mm) detected during first low-dose CT on 24 June 2000. (b) At the second year scan (23 June 2001), the nodule had grown to 8.3 mm, and after positive PET was removed surgically (pT1N0 adenocarcinoma).

View larger version (17K): [in this window] [in a new window]   Figure 2. Size changes in the 24(out of 238) small nodules detected at first CT that had grown during the subsequent 4 years. +Nodules removed surgically and diagnosed as carcinoma.