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Effect of age and gender on the number and distribution of sites in Paget's disease of bone

¹ Department of Diagnostic Imaging and, ² Charles Salt Centre for Human Metabolism, Robert Jones & Agnes Hunt Orthopaedic Hospital, Oswestry, Shropshire SY10 7AG, ³ X-ray Department, Princess Royal Hospital, Telford, Shropshire, UK

View larger version (17K): [in this window] [in a new window]   Figure 1. Graphical representation of the proportion of patients with monostotic disease in patient series investigated by scintigraphy according to year of publication of the data. Note the increase in patients with only one site of Paget's disease of bone. References: Shirazi et al, 1974 [16]; Kanis, 1991 [11]; Meunier et al, 1987 [10]; Salson, 1981 [as quoted in Kanis [11]); Cundy et al, 2004 [1]; Vellenga et al, 1984 [13]; Wellman et al, 1977 [17]; Monfort et al, 1999 [18]; Harinck et al, 1986 [12]; Alvarez et al, 1997 [19]; Morales-Piga et al, 2002 [6]; Merrick and Merrick, 1985 [20]; Gennari et al, 2005 [8]. The data from Morales-Piga et al (2002) [6] represent an average of two groups described in the paper (94/233). The data from Cundy et al (2004) [1] is an average of the percentage with monostotic disease between 1985–1993 (24%) and 1994–2002 (36%).