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First published online February 28, 2007
British Journal of Radiology (2007) 80, 437-445
© 2007 British Institute of Radiology
doi: 10.1259/bjr/34082277

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Value of contrast-enhanced multiphase CT in combined PET/CT protocols for oncological imaging

A C Pfannenberg, MD 1 P Aschoff, MD 1 K Brechtel, MD 1 M Müller, MD 2 M Klein, MD 2 R Bares, MD 2 C D Claussen, MD 1 and S M Eschmann, MD 2

Departments of 1 Diagnostic Radiology and 2 Nuclear Medicine, Eberhard-Karls-University Tuebingen, Hoppe-Seyler- Strasse 3, 72076 Tuebingen, Germany


Figure 1
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Figure 1. 60-year-old female patient with melanoma. (a) Axial PET and (b) fused image showing a focal fluorodeoxyglucose (FDG) uptake in the right lower abdomen, corresponding to the right ascending colon. (c) The axial low-dose CT scan shows some streaking of the pericolic fat in this region but no mass. (d) In the diagnostic CT with intravenous and oral contrast a vascularized tumour lesion could be clearly delineated (arrow) consistent with a bowel metastasis of melanoma (confirmed by histology).

 

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Figure 2. 71-year-old female patient, s/p recent gastric surgery (signet cell carcinoma), interrupted due to bleeding, referral for evaluation of residual disease. (a) Axial PET and (c) fused image demonstrate a hypermetabolic focus centrally in the middle abdomen consistent with residual tumour or a necrotic mesenteric lymph node (white arrow). (d) Contrast-enhanced CT reveals that this focus corresponds to a post-operative abscess with the typical CT pattern. (b) The non-contrast scan cannot establish the correct diagnosis. (h) Diagnostic CT could also detect the enhancing primary gastric tumour (red arrow) which (e,g) is only faintly visible on PET due to poor FDG uptake in signet cell carcinoma. (f) On the non-contrast scan, the tumour can only be suspected.

 

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Figure 3. 46-year-old male patient with lung cancer, re-staging after radiochemotherapy (RCtx) (a–c before and d–f after radiochemotherapy). (a,d) Axial PET scans show decreasing fluorodeoxyglucose uptake after RCtx in the tumour region right lower lobe indicating response to therapy (arrow). (b,e) Although in the non-contrast CT as well as in (c,f) the contrast-enhanced CT the tumour accompanying atelectasis is shown to be disappearing, a progressive mass lesion with infiltration of the left atrium is also visible caused by residual tumour and/or cardiac thrombus, only seen in the contrast-enhanced scan (f, arrow).

 





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