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British Journal of Radiology (2007) 80, 414-421
© 2007 British Institute of Radiology
doi: 10.1259/bjr/23933268
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Precision of computer-aided volumetry of artificial small solid pulmonary nodules in ex vivo porcine lungs

H Bolte, MD 1 C Riede, MD, MSc 1 S Müller-Hülsbeck, MD 1 S Freitag-Wolf, MSc 2 G Kohl, MSc 3 T Drews 1 M Heller, MD 1 and J Bieder, MD 1

1 Department of Diagnostic Radiology, University Hospital Schleswig-Holstein Campus Kiel, Arnold-Heller Strasse 9, 24105 Kiel, 2 Institut of Medical Informatics and Statistics, University Hospital Schleswig-Holstein Campus Kiel Brunswiker-Strasse 10, 24105 Kiel, 3 Siemens Medical Solutions, Siemensstraße1, 91301 Forchheim, Germany


Figure 1
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  		Figure 1. Chest phantom with prepared inserted porcine lung.

 

Figure 2
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  		Figure 2. Graphical user interface of the LungCARE© software showing four small screens (default setting): two axial views, of which one has a set slice thickness of 1 mm (above right) and one represents a thick sliding maximum intensity projection (MIP) of adjustable thickness (above left), a coronal view in which the thickness of the thick sliding MIP can be adjusted (below left) and one view that shows the select volume of interest (VOI, below right). To create a VOI, a nodule is selected with a mouse click. The initial structure of interest is marked by a rectangle. If the observer accepts the positioning of this marker, primary (semi-automatic) volumetry is started.

 

Figure 3
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  		Figure 3. Process of nodule selection and volumetric analysis: (a) marked lesion without volumetric analysis, (b) result of semi-automatic volumetry (the included subvolume is marked homogeneously white), (c) after manual corrected volumetry, all lesion parts are marked.

 

Figure 4
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  		Figure 4. Scatterplot of overall results(n = 202) of semi-automatic volumetry compared with dissected lesion volume.

 

Figure 5
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  		Figure 5. Scatterplot of overall results(n = 202) of manual corrected volumetry compared with dissected lesion volume.

 

Figure 6
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  		Figure 6. Scatterplot of overall results(n = 202) for relative deviation of semi-automatic volumetry compared with dissected lesion volume.

 

Figure 7
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  		Figure 7. Scatterplot of overall results(n = 202) for relative deviation of manual corrected volumetry compared with dissected lesion volume.

 

Figure 8
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  		Figure 8. Scatterplot of relative deviation of semi-automatic volumetry compared with dissected lesion volume for lesions from 5 to 10 mm in diameter (n = 171).

 

Figure 9
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  		Figure 9. Scatterplot of relative deviation of manual corrected volumetry compared with dissected lesion volume for lesions from 5 to 10 mm in diameter (n = 171).

 




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