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First published online June 22, 2006
British Journal of Radiology (2006) 79, 707-711
© 2006 British Institute of Radiology
doi: 10.1259/bjr/22522280

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Quantitative optical coherence tomographic elastography: method for assessing arterial mechanical properties

J Rogowska, PhD 1,2 N Patel, BS 1 S Plummer, BS 1 and M E Brezinski, MD, PhD 1,2

1 Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, 2 Harvard Medical School, Boston, Massachusetts, USA


Figure 1
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Figure 1. A typical optical coherence tomography(OCT) 2% phantom images after applying stress of (b) 0.772 kPa, (c) 1.595 kPa and (d) 2.062 kPa to original phantom (a). The displacement vectors are shown in red.

 

Figure 2
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Figure 2. Young's modulus for 1%, 2%, and 3% phantoms estimated using two techniques: callipers' measurements and OCT elastography. The bars indicate standard deviation. The differences between calliper and OCTE measurements were found to be non-significant (p = 0.6, p = 0.25 and p = 0.38 for 1%, 2% and 3% phantoms, respectively).

 

Figure 3
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Figure 3. Aorta images after applying stress of(b) 0.0355 kPa, (c) 0.0868 kPa and (d) 0.1273 kPa to original image (a). Figure 3aGo indicates location of intima (I), media (M) and glass compression plate (G). The displacement vectors are shown in red.

 

Figure 4
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Figure 4. Axial displacement maps for compressed aorta images shown onFigure 3Go.

 





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