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First published online April 26, 2006
British Journal of Radiology (2006) 79, 659-665
© 2006 British Institute of Radiology
doi: 10.1259/bjr/12699987
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Imaging well-differentiated hepatocellular carcinoma with dynamic triple-phase helical computed tomography

C-S Li 1,3 R-C Chen 1,3,4 H-Y Tu 1 L-S Shih 2 T-A Zhang 2 J-M Lii 1 W-T Chen 1 S-J Duh 1 and L-C Chiang 1

Departments of 1Radiology 2Pathology, Renai Branch, Taipei City Hospital, Taipei 3Department of Radiology, School of Medicine, National Yang-Ming University, Taipei and 4Department of Radiology, School of Medicine, Taipei Medical University, Taipei, Taiwan


Figure 1
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  		Figure 1. Images of a 1.1 cm-diameter well-differentiated hepatocellular carcinoma in segment IV of the liver in a 73-year-old man. (a) Abdominal ultrasound disclosed a hepatic tumour with high echogenicity (arrow). (b,c) The tumour was isodense to surrounding liver parenchyma in unenhanced (not shown), arterial-dominant phase (b) and portal venous phase (c) of dynamic CT and, as a result, could not be identified. (d) Photomicrograph of the needle biopsy specimen showed a well-differentiated hepatocellular carcinoma. Haematoxylin and eosin, original magnification x100.

 

Figure 2
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  		Figure 2. Dynamic CT images of a 1.5 cm-diameter well-differentiated HCC in segment II of the liver in a 43-year-old man. (a) The tumour was hypodense in unenhanced scan (arrow), (b) hyperdense in arterial-dominant phase (arrow) and (c) isodense in portal venous phase. (d) Photomicrograph of the needle biopsy specimen with reticulin stain showed a disorganized reticulin framework with irregular thin-trabecular pattern. Original magnification x100.

 

Figure 3
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  		Figure 3. Dynamic CT images of a 2.1 cm-diameter well-differentiated HCC in segment III of the liver in a 54-year-old man. (a) The tumour was hypodense in unenhanced scan (arrow). (b) Positive enhancement of the tumour was demonstrated in arterial-dominant phase (arrow). (c) In portal venous phase, the tumour was again hypodense (arrow), representing the "low-high-low" pattern on dynamic CT scan.

 




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