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British Journal of Radiology (2006) 79, 24-31
© 2006 British Institute of Radiology
doi: 10.1259/bjr/81790390

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The case for particle therapy

B Jones, MD, FRCR, MedFIPEM

Queen Elizabeth University Hospital, Birmingham B15 2TH, UK


Figure 1
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Figure 1. Schematic depth dose diagram of a proton beam Bragg peak, the spread out Bragg peak and a megavoltage X-ray beam (modified from Suit et al [12]). The grey shaded areas indicate the extent of dose reduction within normal tissues situated proximal and distal to the tumour target.

 

Figure 2
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Figure 2. Approximate depth dose positions of partially spread out Bragg peaks for protons of different energies.

 

Figure 3
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Figure 3. A schematic diagram of a synchrotron treatment centre.

 

Figure 4
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Figure 4. (A–C) Simplified schematic diagrams of protons and (D–F) X-ray percentage depth dose distributions for three simple field arrangements. In B, C, E, F depth is measured along the direction of opposing fields. Relatively small changes in dose are not included in these fields.

 

Figure 5
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Figure 5. (a,b). Axial views of simplified schematic dose distributions for three field coplanar techniques using X-rays and protons.

 

Figure 6
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Figure 6. (a, b) Comparative dose distributions for IMRT and protons for a recurrent sarcoma in a young 12-year-old boy (reproduced by kind permission of Dr A Lomax, PSI, Switzerland and Prof. P Hoskins, Editor of Clinical Oncology).

 

Figure 7
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Figure 7. Comparisons of dose distributions for a 4 field X-ray (photon) plan and a proton plan for treatment of hepatocellular cancer (courtesy of Dr J Munzenrider, Northwest Proton Therapy Centre, Boston, USA).

 

Figure 8
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Figure 8. An example of a single field application of protons to treat a posterior orbital cancer (courtesy of Dr J Munzenrider, Northwest Proton Therapy Centre, Boston, USA). The colours denote different dose levels with red being the full prescribed dose, with fall off to the limits of the beam.

 





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