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Glioblastoma multiforme with atypical diffusion-weighted MR findings

¹ Department of Radiology, Uludag University Medical School, Bursa and ² Bursa State Hospital, Bursa, Turkey

View larger version (54K): [in a new window]   Figure 1. Glioblastoma, left basal ganglia. T1 weighted image (a) low signal intensity of the cystic component and post-contrast T1 weighted image (b) peripheral enhancement after contrast material administration. Diffusion-weighted MR image (c) low signal intensity, typical lesion. Apparent diffusion coefficient (ADC) map (d) depicts high signal intensity of the lesion, ADC value is 2.82 x 10–3 mm2 s–1.

View larger version (50K): [in a new window]   Figure 2. Glioblastoma, right frontal lobe. T1 weighted image (a) apparent low signal intensity and post-contrast T1 weighted image (b) lesion with strong peripheral enhancement after contrast material administration. Diffusion-weighted MR image (c) apparent high signal intensity, atypical lesion. Low signal intensity is visualized on apparent diffusion coefficient (ADC) map (d) with ADC value of 1.13 x 10–3 mm2 s–1.

View larger version (20K): [in a new window]   Figure 3. Apparent diffusion coefficient (ADC) value of the 48 glioblastoma multiforme. The difference between typical and atypical forms of glioblastomas was statistically significant (p<0.001).