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British Journal of Radiology (2005) 78, 758-761
© 2005 British Institute of Radiology
doi: 10.1259/bjr/55106848

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Gluteal injection site granulomas: false positive finding on FDG-PET in patients with non-small cell lung cancer

H Prosch, MD 1 S Mirzaei, MD 2 E Oschatz, MD 1 G Strasser, MD 1 M Huber, MD 3 and G Mostbeck, MD 1

1 Otto Wagner Hospital, Department of Radiology, Sanatoriumsstra{beta}e 2, 1140 Vienna, 2 Wilhelminenspital, Institute of Nuclear Medicine, Montleartstra{beta}e 37, 1160 Vienna and 3 Otto Wagner Hospital, Department of Pathology, Sanatoriumsstra{beta}e 2, 1140 Vienna, Austria



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Figure 1. (a) 57-year-old woman with lung cancer. FDG-PET scan demonstrating pathological tracer accumulation in the right lower dorsal lung (arrowhead) and a hypermetabolic focus in the right dorsal pelvic region (arrows). (b) Ultrasound of the right buttock. Inhomogeneous, partly hyperechogenic and partly hypoechogenic (compared with the surrounding fat) lesion with poorly defined margins (arrowheads) and a maximal diameter of 1.5 cm within the adipose tissue.

 


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Figure 2. (a) 71-year-old man with lung cancer. FDG-PET demonstrating hypermetabolic foci in the left upper and left lower lung suggesting tumour recurrence (mediastinal adenopathy not shown). Hypermetabolic focus on the right side corresponds to posterior parts of the liver. In addition there is a hypermetabolic focus in the right buttock (arrows). (b) US of the right buttock. Poorly marginated, hyperechogenic lesion (1.9 cm diameter) surrounded by a less echogenic rim. (c) Histological image showing an accumulation of macrophages (arrows) within fibrous tissue. Immunostaining for anti-human macrophage CD 68 ( x 250).

 





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