This Article Abstract Full Text Full Text (PDF) Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Bauman, G Articles by Kron, T Search for Related Content PubMed PubMed Citation Articles by Bauman, G Articles by Kron, T

Helical tomotherapy for craniospinal radiation

Departments of ¹ Radiation Oncology and ² Clinical Physics, London Regional Cancer Centre, 790 Commissioners Road East, London, Ontario, N6A 4L6, Canada

View larger version (64K): [in a new window]   Figure 1. Dose–volume histogram for LINAC craniospinal treatment. Esoph: oesophagus; Gut: small/large bowel; CTVb/CTVs: clinical target volume brain and spine; GTVb/GTVs: gross tumour volume brain and spine; PTVb/PTVs: planning target volume for GTV boost brain and spine.

View larger version (15K): [in a new window]   Figure 2. Dose–volume histogram (DVH) for the 25 mm fan beam plan. Excellent coverage of the clinical target volume (CTV) (craniospinal axis) with 36 Gy and the gross tumour in the cord and brain (gross target volume (GTV) with 45 Gy. Doses to critical structures (OAR) are below specified limits. Compared with the DVH for LINAC treatment (1b), variation within the GTV and CTV for brain and spine is much less and OAR doses are overall much lower. For paired organs (Lung, Kidney) only the side with the higher (i.e. least favourable) DVH is illustrated.

View larger version (81K): [in a new window]   Figure 3. 25 mm helical tomotherapy plan demonstrating excellent conformality in sagittal plane. The chosen fan beam width thickness results in compromises in cribiform plate coverage in order to respect eye dose volume constraints (Inset 2).

View larger version (73K): [in a new window]   Figure 4. Helical tomotherapy plan using 10 mm fan beam width for cranial treatment. Improved coverage of the cribiform plate area is evident.