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British Journal of Radiology (2005) 78, 355-357
© 2005 British Institute of Radiology
doi: 10.1259/bjr/36150185
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The reverse target sign in liver disease: a potential ultrasound feature in cirrhotic liver nodules characterization

G J Kraus, MD1, P Schedlbauer, MD1, S Lax, MD2, D Zebedin, MD3 and F Flueckiger, MD1

Institutes of 1 Radiology and 2 Pathology, General Hospital Graz-West, Goestingerstrasse 22, 8020 Graz and 3 Department of Radiology, University Hospital Graz, Auenbruggerplatz 1, 8036 Graz, Austria



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  		Figure 1. Ultrasound (B-mode) shows disseminated isoechoic to hyperechoic macronodular lesions with a hyperechoic rim (reverse target sign) throughout the liver parenchyma.

 


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  		Figure 2. On an unenhanced spiral CT-scan, the lesions are isodense to liver parenchyma with a hypoattenuating rim.

 


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  		Figure 3. Histology: regenerative nodule with fibrocirrhotic changes (white arrows) surrounding partly steatotic hepatocytes (black arrows) (Chronotrop-Aniline-Blue stain, magnification 40 x ).

 




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