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Pilomatrix carcinoma of the axilla: CT and MRI features

Departments of ¹ Radiology, ² Orthopaedic Surgery, ³ Pathology, Kanagawa Cancer Centre, 1-1-2 Nakao, Asahi-ku, Yokohama, 241-0815, ⁴ Depatment of Radiology, Yamato Tokusyukai Hospital, 4-4-12, Chuou, Yamato, 242-0021 and ⁵ Department of Radiology, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan

View larger version (117K): [in a new window]   Figure 1. 54-year-old man with left axillar mass. (a) Plain radiograph shows a soft tissue mass with amorphous dotted calcifications in the left axilla (arrows). (b) Coronal multiplanar reformated CT image (window width=250 HU, window level=50 HU) after administration of intravenous contrast material shows a well-circumscribed mass with multiple small calcifications and cystic components (arrows). (c) Axial T1 weighted MR image shows a diffusely inhomogeneous mass with a mixture of low signal intensity and slightly high signal intensity areas. (d) Axial T2 weighted MR images shows a mixture of high signal intensity and low signal intensity areas. ) (e) Axial T1 weighted image after intravenous administration of gadolinium contrast agent (gadopentetate dime–glumine) shows diffusely inhomogeneous enhancement (arrows).

View larger version (99K): [in a new window]   Figure 2. Pathological findings. (a) Cut surface of the excised specimen shows a multinodular mass with calcifications (arrowheads) and cystic components (arrows). (b) Microscopic examination shows a proliferation of basophilic cells (arrowheads) and shadow cells (arrow) (haematoxylin and eosin (H&E) x 40). (c) The tumour cells show pleomorphism, vesicular nucleus, mitoses, and prominent nucleoli (H&E x 400).