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British Journal of Radiology (2005) 78, 122-129
© 2005 British Institute of Radiology
doi: 10.1259/bjr/30866348
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In vivo validation of a novel semi-automated method for border detection in intravascular ultrasound images

C V Bourantas, MD 1,3 M E Plissiti, MSc 2 D I Fotiadis, PhD 2,3 V C Protopappas, MSc 2 G V Mpozios, PhD 1,3 C S Katsouras, MD 1,3 I C Kourtis, BSc 2 M R Rees, FRCP, FRCR 4 and L K Michalis, MD, MRCP 1,3

1 Department of Cardiology, Medical School, 2 Unit of Medical Technology and Intelligent Information Systems, Department of Computer Science, University of Ioannina, 3 Michailideion Cardiology Center, GR 45110 Ioannina, Greece and 4 University Department of Clinical Radiology, Bristol Royal Infirmary, Bristol BS2 8HW, UK



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  		Figure 1. Two borders with the same area and perimeter value corresponding to geometrically different regions of interest. X indicates ratio of non-overlapping areas.

 


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  		Figure 2. In figures (a) and (b) the non-overlapping areas are the same. The similarity in two border estimations is higher in figure (a) where the Hausdorff and the mean distance have the same value than in figure (b) where Hausdorff is larger than mean distance.

 


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  		Figure 3. The interobserver variability between the contour detection method and the two observers for the lumen area. SD, standard deviation.

 


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  		Figure 4. The interobserver variability between the contour detection method and the two observers for the external elastic membrane area. SD, standard deviation.

 


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  		Figure 5. The interobserver variability between the contour detection method and the two observers for the stent area. SD, standard deviation.

 


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  		Figure 6. Linear regression analysis of the automatic lumen area vs manual tracing.

 


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  		Figure 7. Linear regression analysis for the external elastic membrane area between the automatic and manual tracing.

 


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  		Figure 8. Linear regression analysis of the automatic stent area vs manual tracing.

 


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  		Figure 9. The interobserver variability between our method and the two observers concerning the non-overlapping areas for the lumen borders. SD, standard deviation.

 


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  		Figure 10. The interobserver variability between our method and the two observers concerning the non-overlapping areas for the external elastic membrane borders. SD, standard deviation.

 


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  		Figure 11. The interobserver variability between our method and the two observers concerning the non-overlapping areas for the stent borders. SD, standard deviation.

 


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  		Figure 12. Stent border detection in an intravascular ultrasound frame by (a) an expert observer and by (b) our automated segmentation method.

 




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