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British Journal of Radiology (2004) 77, 1000-1006
© 2004 British Institute of Radiology
doi: 10.1259/bjr/69059431
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In search of an unknown primary tumour presenting with extracervical metastases: the diagnostic performance of FDG-PET

U Joshi, MD1, J J M van der Hoeven, MD1,3, E F I Comans, MD, PhD1, G J Herder, MD1, G J J Teule, MD, PhD1 and O S Hoekstra, MD, PhD1,2

Departments of 1 Nuclear Medicine and PET Research and 2 Clinical Epidemiology and Biostatistics, VU University Medical Centre, Amsterdam and 3 Department of Internal Medicine, Amstelveen Hospital, Amstelveen, The Netherlands



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  		Figure 1. True positive FDG-PET. Patient 62: 70-year-old male with bone metastases. Besides multiple bone metastases (vertebrae, humerus, chest wall), PET revealed markedly increased uptake in the thyroid (arrow). Thyroidectomy confirmed a papillary thyroid carcinoma.

 


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  		Figure 2. False positive FDG-PET. Patient 41: 48-year-old female with cerebral metastases. PET demonstrates increased uptake in the right breast (abscess, misinterpreted as the primary tumour, small arrow) as well as the right lung (primary tumour, misinterpreted as metastasis, large arrow).

 


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  		Figure 3. Multiple positive foci. Patient 11: 56-year-old male with mediastinal lymphadenopathy (biopsy difficult). PET demonstrates multiple foci of increased uptake (left pleura, possible separate focus in left lung, mediastinum, ribs, vertebrae). A rib biopsy based on PET (arrow) revealed small cell lung cancer.

 




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