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British Journal of Radiology (2004) 77, 257-260
© 2004 British Institute of Radiology
doi: 10.1259/bjr/69516821
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False positive fluorine-18 fluorodeoxy-D-glucose positron emission tomography finding caused by osteoradionecrosis in a nasopharyngeal carcinoma patient

S-H Liu, MD 1 J T Chang, MD 2 S-H Ng, MD 3 S-C Chan, MD 1 and T-C Yen, MD, PhD 1

Departments of 1 Nuclear Medicine, 2 Radiation Oncology and 3 Diagnostic Radiology, Chang Gung Memorial Hospital and University, 5 Fu-Hsing Street, Kweishan Taoyuan 333, Taiwan



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  		Figure 1. The contrast-enhanced MRI images, (a) coronal view, (b) transverse view, revealed a soft tissue lesion in the nasopharynx with bony destruction in the skull base (arrowhead). The lesion was more prominent than before. Therefore, recurrent tumour was highly suspected.

 


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  		Figure 2. The whole body FDG PET scan was performed at 40 min after intravenous injection of 370 MBq (10 mCi) of 18F-FDG. One focal area of significant FDG-6-phosphate accumulation in the right skull base region was noted (arrow). The delayed imaging was performed 3 h after injection. (a) Coronal view, (b) transverse view; SUVmax in early and delayed images were 5.1 and 5.3, respectively. The lesion was later debrided and proved to be osteoradionecrosis without malignant cells histologically.

 


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  		Figure 3. In order to rule out the possibility of inaccurate siting of the surgery, FDG PET scan was performed again 2 months after debridement, (a) coronal view, (b) transverse view. No treatment for cancer was prescribed between the two scans. The scan revealed that the previous FDG avid lesion had disappeared.

 




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