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British Journal of Radiology (2003) 76, S36-S42
© 2003 British Institute of Radiology
doi: 10.1259/bjr/18486642

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Perfusion CT for the assessment of tumour vascularity: which protocol?

K A Miles, MSc, FRCR, MD

Division of Clinical and Laboratory Investigation, Brighton & Sussex Medical School, University of Sussex, Falmer, Brighton BN1 9PX, UK



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Figure 1. Time–attenuation curves from tumours are determined by the contrast material in the intravascular and extravascular compartments. During the first pass, the contrast material is predominantly intravascular and contrast enhancement reflects perfusion and blood volume. Delayed enhancement is determined by the passage of contrast material into and out of the extravascular space, as determined by rate constants k1 and k2.

 





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