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British Journal of Radiology (2003) 76, 880-884
© 2003 British Institute of Radiology
doi: 10.1259/bjr/18937619
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Pulmonary lesions associated with Sjögren's syndrome: radiographic and CT findings

N Matsuyama, MD 1 K Ashizawa, MD 1 T Okimoto, MD 1 J Kadota, MD 2 H Amano, MD 3 and K Hayashi, MD 1

1 Department of Radiology, 2 2nd Department of Internal Medicine and 3 Institute of Tropical Medicine, Nagasaki University School of Medicine, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan



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  		Figure 1. 49-year-old woman with primary Sjögren's syndrome. (a) Chest radiograph shows bilateral linear and reticular opacities, ground-glass opacity as well as lung cysts. These opacities are dominant in lower lung field. (b, c) Thin-section CT scans obtained at two levels. Peribronchovascular interstitial thickening, interlobular septal thickening, centrilobular abnormalities and ground-glass opacity are seen. In addition, multiple lung cysts are demonstrated. This case was classified as lymphoproliferative disorder pattern. Pathological diagnosis of lymphoid interstitial pneumonia was obtained.

 


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  		Figure 2. 63-year-old woman with secondary Sjögren's syndrome (polymyositis/dermatomyositis). (a) Chest radiograph shows bilateral linear and reticular opacities and ground-glass opacity predominantly in both lower lung fields. (b) Thin-section CT scan obtained at lung base. Intralobular interstitial thickening, ground-glass opacity, honeycombing and traction bronchiectasis are demonstrated. This case was classified as IP pattern. Pathological diagnosis of usual interstitial pneumonia was obtained.

 


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  		Figure 3. 71-year-old woman with secondary Sjögren's syndrome (progressive systemic sclerosis). Thin-section CT scan obtained at lung base. Interlobular septal thickening, intralobular interstitial thickening and traction bronchiectasis are seen. In addition to these findings, multiple lung cysts are demonstrated. This case was classified as interstitial pneumonia pattern and pathological diagnosis of usual interstitial pneumonia was made.

 


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  		Figure 4. 70-year-old woman with primary Sjögren's syndrome. Thin-section CT scan obtained at the level of aortic arch. Centrilobular abnormalities and bronchiolectasis are seen. This case was classified as bronchiolitis pattern.

 




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