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Power Doppler ultrasound of rheumatoid synovitis: quantification of therapeutic response

Department of Radiology, Nuffield Orthopaedic Centre, Windmill Road, Headington, Oxford OX3 7LD, UK

View larger version (99K): [in a new window]   Figure 1. Pre-treatment power Doppler ultrasound scan of a middle finger metacarpo-phalangeal joint showing synovial hypertrophy and increased vascularity.

View larger version (99K): [in a new window]   Figure 2. Post-treatment power Doppler ultrasound scan (of the same patient as Figure 1), demonstrating a significant decrease in synovial hypertrophy and vascularity.

View larger version (18K): [in a new window]   Figure 3. The power Doppler spectrum, representing power Doppler quantity over time. Pre- and post-treatment spectra are compared for the same patient.

View larger version (17K): [in a new window]   Figure 4. High–low graph demonstrating the mean power Doppler quantity pre- and post-treatment for each patient.

View larger version (12K): [in a new window]   Figure 5. Graph demonstrating the close correlation (p=0.012) between the percentage change in mean Doppler quantity with the percentage change in Stanford Health Assessment Questionnaire (HAQ) score.