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British Journal of Radiology (2003) 76, 301-308
© 2003 British Institute of Radiology
doi: 10.1259/bjr/32889803
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X-ray refraction effects: application to the imaging of biological tissues

R A Lewis, PhD 1 C J Hall, PhD 1 A P Hufton, PhD 2 S Evans, MSc 3 R H Menk, PhD 4 F Arfelli, PhD 5 L Rigon, MS 4 G Tromba, PhD 4 D R Dance, PhD 3 I O Ellis, FRCPath 6 A Evans, FRCR 6 E Jacobs, MSc 7 S E Pinder, FRCPath 6 and K D Rogers, PhD 8

1 Daresbury Laboratory, Warrington WA4 4AD, UK, 2 North Western Medical Physics, Christie Hospital NHS Trust, Manchester M20 4BX, UK, 3 Joint Department of Physics, The Royal Marsden NHS Trust, London SW3 6JJ, UK, 4 Sincrotrone Trieste Società Consortile per Azioni, Basovizza, Italy, 5 Department of Physics, Università di Trieste, Italy, 6 City Hospital, Nottingham NG5 1PB, UK, 7 Cancer Studies Unit, Queens Medical Centre, Nottingham, UK and8 Department of Materials and Medical Sciences, Cranfield University, Swindon SN6 8LA, UK



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  		Figure 1. Experimental set up for diffraction enhanced imaging (not to scale).

 


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  		Figure 2. Images of a mouse liver: (a) conventional image; (b) image taken at the peak of the rocking curve; and (c) refraction image. Zoomed sections of the peak and refraction images give a clearer depiction of the level of detail present.

 


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  		Figure 3. Images of mouse lungs: (a) conventional image; (b) image taken at the peak of the rocking curve; (c) refraction image; and (d) image taken at the 10% reflectivity point on the rocking curve. Zoomed sections of the peak and refraction images give a clearer depiction of the level of detail present.

 


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  		Figure 4. Images of a mouse heart: (a) conventional image; (b) image taken at the peak of the rocking curve; and (c) refraction image.

 


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  		Figure 5. Images of a mouse leg: (a) conventional image; (b) image taken at the peak of the rocking curve; and (c) refraction image. Zoomed sections of the peak and refraction images give a clearer depiction of the level of detail present.

 




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