Bone complications in children with Gaucher disease
B Bembi, MD1,
G Ciana, MD1,
E Mengel, MD2,
M R Terk, MD3,
C Martini1 and
R J Wenstrup, MD4
1 Burlo Garofolo Institute, Trieste, Italy, 2 Children's Hospital of the Johannes-Gutenberg University, Mainz, Germany, 3 Keck School of Medicine, University of Southern California, USA and 4 Children's Foundation Research Hospital, Cincinnati, Ohio, USA
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Figure 1. Developmental conversion of red to yellow marrow in the femur (ages are in years) [12]. Reproduced, with permission of theRadiological Society of North America, from: Moore SG, Dawson KL. Red and yellow marrow in thefemur: age-related changes in appearance at MR imaging. Radiology 1990;175:219–23.
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Figure 2. Lumbar vertebra bone mineral density (BMD) Z scores for paediatric patients at the Gaucher Disease Treatment Center in Cincinnati according to age.
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Figure 3. Lumbar vertebra bone mineral density (BMD) Z scores for paediatric patients at the Gaucher Disease Treatment Center in Cincinnati according to year of treatment. ERT, enzyme replacement therapy.
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Figure 4. Bone mineral density Z scores for the distal ulna before and after 18–24 months of treatment at the Children's Hospital of the Johannes-Gutenberg University.
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Copyright © 2002 by the British Institute of Radiology.
