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Pre-operative staging of invasive breast cancer with MR mammography and/or PET: boon or bunk?

Departments of ¹ Diagnostic Radiology and ² Nuclear Medicine, University of Ulm, Robert-Koch-Str. 8, 89081 Ulm and ³ Department of Obstetrics and Gynecology, University of Ulm, Prittwitzstr. 43, 89081 Ulm, Germany

View larger version (77K): [in a new window]   Figure 1. (a) Magnetic resonance mammogram of a 49-year-old patient with suspected carcinoma of the right breast. (b) The lesion was not visualized by positron emission tomography. Histology revealed an invasive lobular carcinoma with a diameter of 1.3 cm x 3.0 cm.

View larger version (71K): [in a new window]   Figure 2. Extensive unifocal mammary carcinoma of the right breast in a 52-year-old patient. The findings of (a) magnetic resonance mammography, (b) positron emission tomography and histology are in agreement.

View larger version (78K): [in a new window]   Figure 3. Corresponding findings at both (a) magnetic resonance mammography (MRM) and (b) positron emission tomography (PET) showing a 5 cm tumour in a 37-year-old patient with mammary carcinoma of the left breast. Histology revealed both an invasive lobular mammary carcinoma and extensive, non-invasive portions. The entire volume of the tumour was revealed at histology to be approximately 10 cm in diameter. Neither MRM nor PET correctly visualized this tumour.