Peripheral primitive neuroectodermal tumour during pregnancy
H Varveris, MD, PhD1,
M Mazonakis, MSc, PhD2,
J Damilakis, MSc, PhD2,
K Stefanaki, MD, PhD3,
E Lyraraki, MD1,
S Kachris, MD1,
E Orfanoudaki, MD4,
P Prassopoulos, MD, PhD1 and
G Samonis, MD, PhD5
Departments of 1 Radiotherapy & Oncology, 2 Medical Physics, 3 Histopathology, 4 Obstetrics and Gynecology and 5 Clinical Oncology, Iraclion University Hospital, School of Medicine, 71110 Iraclion, Crete, Greece
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Figure 1. Sagittal T1 weighted MR image after intravenous contrast medium. An extensive enhancing lytic mass is shown in the skull in the parietal-occipital region. The lesion infiltrates the meninges (which are enhanced) and invades the right hemisphere (arrowhead).
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Figure 2. Diffuse infiltration of small round cells within the intervillous space without any infiltration of the decidua. Homer–Wright rosettes are seen, H-E stain at x 200 magnification.
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Figure 3. Diffuse, strong membrane expression of CD-99/MIC-2 (O-13) in the neoplastic cells invading the placenta. Streptavidin-biotin peroxidase stain at x 400 magnification.
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Figure 4. (a) Sagittal T2 weighted and (b) post-gadolinium T1 weighted MR images of the lumbar spine. The patchy areas of high signal on T2 weighted images (a) in vertebral bodies correspond to bone marrow infiltration and oedema, with enhancement on post-gadolinium images (b). Enhancement of the meninges and small epidural soft tissue masses (arrowheads) show extension into the spinal canal.
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Copyright © 2002 by the British Institute of Radiology.
